JSTRING: A Novel Java Tandem Repeats Searcher in Genomic Sequences with an Interactive Graphic Output
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JSTRING: A Novel Java Tandem Repeats Searcher in Genomic Sequences with an Interactive Graphic Output
The search of Tandem Repeats in a genomic sequence is of growing interest but unfortunately the existing tools have the drawback of producing cumbersome results that require a painstaking interpretation. In order to help users interpret the results at first glance, we implemented JSTRING that shows the results also in a very clear graphic format, thus allowing their immediate survey. The softwa...
متن کاملSTRING: finding tandem repeats in DNA sequences
MOTIVATION AND RESULTS The importance of Tandem Repeats in some genomes is now well established. We have reported elsewhere some interesting new results obtained by means of a preliminary program for finding Tandem Repeats in DNA sequences, together with a brief description of the basic ideas of the algorithm. We describe here a completely new program based only in part on those ideas, we brief...
متن کاملFiltering Tandem Repeats in DNA Sequences
A tandem repeat is a sequence of two or more contiguous, approximate copies of a pattern. Tandem repeats occur in the genomes of both eukaryotic and prokaryotic organisms. They are important in numerous fields including disease diagnosis, mapping studies, human identity testing (DNA fingerprinting), sequence homology, and population studies. Although tandem repeats have been used by biologists ...
متن کاملStatistical Approaches to Detecting and Analyzing Tandem Repeats in Genomic Sequences
Tandem repeats (TRs) are frequently observed in genomes across all domains of life. Evidence suggests that some TRs are crucial for proteins with fundamental biological functions and can be associated with virulence, resistance, and infectious/neurodegenerative diseases. Genome-scale systematic studies of TRs have the potential to unveil core mechanisms governing TR evolution and TR roles in sh...
متن کاملTandem repeats finder: a program to analyze DNA sequences.
A tandem repeat in DNA is two or more contiguous, approximate copies of a pattern of nucleotides. Tandem repeats have been shown to cause human disease, may play a variety of regulatory and evolutionary roles and are important laboratory and analytic tools. Extensive knowledge about pattern size, copy number, mutational history, etc. for tandem repeats has been limited by the inability to easil...
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ژورنال
عنوان ژورنال: The Open Applied Informatics Journal
سال: 2008
ISSN: 1874-1363
DOI: 10.2174/1874136300802010014